AP Bio Character and Cast Guide

The former NBC sitcom AP Biography has a robust cast full of hilarious main and supporting characters. Mike O’Brien’s Saturday night live acclaim created the original sitcomwhich premiered on February 1, 2018. The show centers on high school teacher-turned-teacher Jack Griffin, played by Glenn Howerton of It’s always sunny in Philadelphia. AP Biography follows Jack as he goes from being a philosophy professor at Harvard University to being an advanced biology professor at his hometown high school, after being disgraced over a YouTube video.

AP Biography ran for two seasons on NBC before moving to Peacock in its final two seasons. The series has been canceled twice, although it has maintained an impressive Rotten Tomatoes score of 88%, with its second and third seasons earning perfect 100% scores from critics. Despite positive reviews from AP Bio, there was not enough consistent viewership for the series to continue for the last four seasons. Over its four-year period, AP Biography featured several notable guest stars and cameos, making it one of the most underrated comedies in recent memory.

Glenn Howerton as Jack Griffin

Actor: Glenn Howerton, 48, is an American actor who was born in Japan. He is best known for playing Dennis Reynolds on the hit FX comedy series. It’s always sunny in Philadelphia, which is the longest-running original comedy series in television history. Howeton co-created the series with co-star Rob McElhenney. Howerton made his film debut in 2005 Must love dogs and also appeared in films such as Crank, The strangers, Everything must go, The huntand Blackberry. Howerton’s other notable television performances include That 80s show (2002), The Mindy Project (2012–2017), Fargo (2014), and Velma (2023-2024).

Notable works:

Character: Howerton stars as main character Dr. Jack Griffin in AP Biography.

Lyric Lewis as Stef Duncan

Actor: Lyric Lewis, 39, is an American actress and writer from New Orleans, Louisiana. Lewis is best known for Waffles + Mochi, crazy TVand the Dreamworks series Curses! on AppleTV+. She has made guest appearances in several notable comedy series and sitcoms, including but not limited to Brooklyn Nine-Nine, Baskets, iCarly, Party downand Night Court. She has also made several appearances as herself on television shows such as History of drunkenness, Is it cake?and The wheel. Lewis set to star in upcoming short film I’m a gigantosaurus, actually alongside Alison Brie.

Notable works:

Character: Lewis stars as history teacher Stef Duncan in AP Biography.

Mary Sohn as Mary Wagner

Actor: Mary Sohn, 44, is an American actress from Illinois. Sohn is best known for her roles in The boss, Between Two Ferns: The Film, Love, Grace and Frankieand Comedy Bang! Bang!. She recently appeared on an episode of Control your enthusiasm and on the TBS series Miracle Workers. She rose to prominence after starring in an episode of the notable HBO comedy series Hello ladies in 2013. She also starred in episodes of Teachers, Superior Donuts, Shrinkand Billion Dollar Estate$.

Notable works:

Character: Sohn plays art teacher Mary Wagner in AP Biography.

Jean Villepique as Michelle Jones

Actor: Jean Villepique is an American actress from New Jersey who studied at Northwestern University. As a former member of The Second City, she is best known for her roles in BoJack Knight and Up all night. She made her television debut in 2007 in episodes of 30 rock and Control your enthusiasm. She also starred alongside Jason Segel and Paul Rudd in the 2009 comedy I love you, man. She has starred in many notable comedy series such as Modern Family, Workaholics, Grey’s Anatomy, Baskets, New girland Better call Saul. She is also known for playing Gretchen in Sharp objects.

Notable works:

Character: Villepique plays home economics teacher Michelle Jones in AP Biography.

Paula Pell as Helen Henry Demarcus

Actor: Paula Pell, 61, is an American comedy writer, producer, and actress from Illinois. Pell is a prolific writer of Saturday night live who has writing credits for over 315 SNL episodes between 1995 and the present day. As an actress, Pell appeared in Parks and Recreation, 30 rock, Anchor 2, From the inside out, The Mindy Project, Unbreakable Kimmy Schmidt, and Inside Out 2. She also voiced several roles in the Netflix animated series Big mouth. She is set to star alongside Matt Berry, Bill Hader and Quinta Bronson in the upcoming The cat in the hat film, as well as Summer of 69 with Chloe Fineman, Charlie Day and Natalie Morales.

Notable works:

Character: Pell plays school administrator Helen Henry Demarcus in AP Biography.

Patton Oswalt as Director Ralph Durbin

Actor: Patton Oswalt, 55, is an American comedian and actor from Virginia who has over 250 professional acting credits to his name. He is best known for his roles in Ratatouille, Young adult, The Secret Life of Walter Mittyand Looking for a friend for the end of the world. He recently appeared in Hacks, Manhunt, Ghostbusters: Frozen Empire, Family Guy, What we do in the shadowsand 80 for Brady. He is also an award-winning stand-up comedian who has been nominated for 4 Emmys, with a win for Best Writing for a Variety Special in 2016. Talking to clap.

Notable works:

Character: Oswalt plays director Ralph Durbin in AP Biography.

AP Bio Cast and Supporting Characters

Aparna Brielle as Sarika: Brielle is best known for FUBAR and Mecha Cadets.

Nick Peine as Marcus: Peine is best known for Office Christmas Party and Just getting started.

Allisyn Snyder as Heather: Snyder is best known for Astrid Trevo and Meet Dave.

Eddie Leavey as Anthony: Leavey is best known for Better. World. Weekend. Always. and Those who cannot.

Jacob Houston as Victor: Houston is best known for Yellow Jackets and The best of Los Angeles.

Sari Arambulo as Grace: Arambulo is best known for Alexa and Katie and Party of Five.

Spence Moore II as Dan Decker: Moore is best known for Creed III and We are who we are.

Marisa Baram as Marissa: Baram is best known for Henry Danger and Real Hollywood Husbands.

Miguel Lee as Eduardo: Lee is best known for David and The savior.

Charlie McCrackin as Coach Dick Novak: McCracking is best known for Intergalactic Radio and Unstable.

AP Bio Cameo Guide

Nikki Glaser as Chloe from Baltimore: Glaser is best known for Shipwreck and Tom Brady’s Roast.

Niecy Nash as Kim Burke: Nash is best known for Reno 911! and Guess who.

Taran Killam as Mr. Vining: Killam is best known for Saturday night live and 12 years of slavery.

Mark Proksch as Philip: Proksch is best known for Better call Saul and What we do in the shadows.

Christopher Lloyd as Melvin: Lloyd is best known for Back to the future and The Addams Family.

Jon Lovitz as Robin Schwonk: Lovitz is best known for A league of its own and Rat race.

Ron Funches as Hans: Funches is best known for Trolls and Inside Out 2.

Angela Kinsey as Brenda: Kinsey is best known for The office and has a special appearance AP Biography.